Initiative / EClipSE

Epidemiological Clinicopathological Studies in Europe
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Epidemiological Clinicopathological Studies in Europe

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Studies 3
The aim of EClipSE is to address the lack of statistical power within individual studies for specific analyses assessing relationships between data collected during life (e.g., health, cognitive, psychological, and genetic) and neuropathology at death.
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Members

Affiliated Members
Investigators Contacts
  • Prof. Carol Brayne
    University of Cambridge

General Information

Year created
2007
Types of cohorts
  • Population cohort
Countries
  • United Kingdom
  • Finland
Setting
International
Funding
This project has received funding from the BUPA Foundation Grant RHAD/094, October 2007-April 2009; EU Marie Curie International Incoming Fellowship (Dr Keage), 2009-2011 and National Health and Medical Research Council of Australia Clinical Overseas Postdoctoral Training Fellowship (Dr Keage), 2011-2013.
Criteria of cohort's to be included
European population-based longitudinal cohorts of older adults with a brain-donation program at death
Health topic
  • Ageing
  • Mental health
  • Neurological diseases
  • General epidemiology
  • Genetics
Socio-environmental context
  • NA

Participants

Number of participants

Total
987
With harmonized data
987

Age range of the samples

Minimum age
65
Maximum age
150

Methodology for harmonization and integration

Strategy of harmonization
Ex-post
Data processing methods
  • NA
    • Type of infrastructure
    Some centrally, other locally
    Integrative data analysis
    • Pooled analyses
    Software
  • Stata
    • Supplementary information
    The number of participants can increase because of future donations.
    More information: EClipSE Collaborative Members. Cohort profile: Epidemiological Clinicopathological Studies in Europe (EClipSE). Journal of Alzheimer’s Disease 18 (2009) 659–663

    Number of cohorts

    Total
    3
    With harmonized data
    3
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)
    1,000

    Access

    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    CC75C Cambridge City over-75s Cohort study Population cohort 2,166
    CFAS Cognitive Function and Ageing Study (CFAS) Population cohort 13,004
    Vantaa 85+ Vantaa 85+ Population cohort 601