Initiative / GenomEUtwin

GenomEUtwin

GenomEUtwin

Studies 7
The aim of GenomEUtwin is to develop novel strategies to maximally utilize the unique features of twin cohorts, including the availability of longitudinal data and sample information about lifestyle and environmental factors, in the characterization of complex traits.
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Investigators Contacts

General Information

Year created
2002
Types of cohorts
  • Population cohort
Countries
  • Denmark
  • Finland
  • Italy
  • Netherlands
  • Norway
  • United Kingdom
  • Australia
  • Sweden
Setting
International
Funding
This project has received funding from the Framework 5th Programme of the European Community.
Criteria of cohort's to be included
Twin cohorts with genomic, lifestyle and environmental information.
Health topic
  • Environmental health
  • Social environment
  • Genetics
Socio-environmental context
  • NA

Participants

Number of participants

Total
1,190,000

Age range of the samples

Minimum age
20
Maximum age
85

Methodology for harmonization and integration

Strategy of harmonization
Ex-post
Data processing methods
  • NA
  • Type of infrastructure
    Data are in different locations
    Integrative data analysis
    • Pooled analyses
    • Federated analyses
    Software
  • Other
  • Supplementary information
    More information: Peltonen l. GenomEUtwin: A Strategy to Identify Genetic Influences on Health and Disease. Twin Research, 2003. Volume 6 Number 5 pp. 354± 360 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/F8439F1D0E19810C93000E07EA51B119/S1369052300003986a.pdf/data_modeling_and_data_communication_in_genomeutwin.pdf Peltonen, L., Perola, M., Boomsma, D. I., Christensen, K., Evans, A., Harris, J., ... Syvanen, A. C. (2003). GENOMEUTWIN - an integrated project of eight large twin cohorts for genetic studies on complex traits. American Journal of Human Genetics, 73, 1330. https://doi.org/10.1086/380311

    Number of cohorts

    Total
    9
    With harmonized data
    9
    Will more cohorts be harmonized?

    Access

    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    DTR The Danish Twin Registry Population cohort 85,000
    FTC The finish twin cohort Population cohort 14,000
    ITR The Italian Twin Registry Population cohort 9,000
    NTP- NIPH The Norwegian Twin Panel Population cohort 14,742
    STR The Swedish Twin Registry Population cohort 87,000
    TRA Twins Research Australia (formerly known as the Australian Twin Registry) Population cohort 45,032
    TwinsUK The St Thomas’ UK Adult Twin Registry Population cohort 14,274