Cognition and Neocortical Volume After Stroke Study
Initiatives
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The study aims to establish whether brain volume change is associated with poststroke dementia, and to elucidate potential causal mechanisms, including genetic markers, amyloid deposition and vascular risk factors. An understanding of whether - and in whom - stroke is neurodegenerative is critical for the strategic use of potential disease-modifying therapies.
*Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.*
- Start Year
- 2014
- End Year
- 2017
| Investigators | Contacts |
|---|---|
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Design
- Study design
- Patients' cohort
- Follow Up
- Participants were followed up at three-months, 12 months and three years.
Marker Paper
Brodtmann A, Werden E, Pardoe H, Li Q, Jackson G, Donnan G, Cowie T, Bradshaw J, Darby D, Cumming T. Charting cognitive and volumetric trajectories after stroke: protocol for the Cognition And Neocortical Volume After Stroke (CANVAS) study. Int J Stroke. 2014 Aug;9(6):824-8. doi: 10.1111/ijs.12301. Epub 2014 Jun 3. .
PUBMED 24894387
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 135
- Number of participants with biosamples
- Supplementary Information
- Over 18 years old. 3 (Melbourne hospital stroke units)
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |