Cardiovascular Health Study
Initiatives
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The objectives of CHS are:
1. To quantify associations of conventional and hypothesized risk factors with CHD and stroke.
2. To assess the association of indicators of subclinical disease, identified by noninvasive measures such as carotid ultrasonography and echocardiography, with the incidence of CHD and stroke.
3. To quantify the association of conventional and hypothesized risk factors with subclinical disease.
4. To characterize the natural history of CHD and stroke, and identify factors associated with clinical course.
5. To describe the prevalence and distributions of risk factors, subclinical dis- ease, and clinically diagnosed CHD and stroke.
**Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.**
- Start Year
- 1987
- Funding
- CHS Research Resources for the Cardiovascular Health of Older Adults (HL130114): 5/17/2016 - 4/30/2021
Visit CHS
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Design
- Study design
- Population cohort
- Follow Up
- Between enrollment and 1998-99, participants were seen in the clinic annually, and contacted by phone at 6-month intervals to collect information about hospitalizations and potential cardiovascular events. Major exam components were repeated during annual follow-up examinations through 1999. From 2000 to present follow-up has been carried out through twice yearly telephone contacts. Between April 2005 and April 2006, CHS participants in the CHS All Stars Study were seen in person or by phone to assess physical and cognitive function.
Marker Paper
Fried LP, Borhani NO, Enright P, Furberg CD, Gardin JM, Kronmal RA, Kuller LH, Manolio TA, Mittelmark MB, Newman A, et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol. 1991 Feb;1(3):263-76. doi: 10.1016/1047-2797(91)90005-w.
PUBMED 1669507
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 5,888
- Number of participants with biosamples
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |
Availability of access information
On the study website : https://chs-nhlbi.org/