De Maastricht Studie
Initiatives
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It aims to identify determinants of the development and progression of
* T2DM;
* its classic complications(cardiovascular disease, retinopathy, neuropathy and nephropathy);
* its emerging comorbidities, such as cognitive decline, depression, and gastrointestinal, musculoskeletal and respiratory diseases. In addition, the impact of this clustering of comorbidities on quality of life and use of health care resources will be defined.
- Start Year
- 2010
- End Year
- 2017
- Funding
- European Regional Development Fund as part of OP-ZUID, the province of Limburg, the department of Economic Affairs of the Netherlands (grant 31O.041), Stichting the Weijerhorst, the Pearl String Initiative Diabetes, the Cardiovascular Center Maastricht, Cardiovascular Research Institute Maastricht (CARIM), School for Nutrition, Toxicology and Metabolism (NUTRIM), Stichting Annadal, Health Foundation Limburg and by unrestricted grants from Janssen, NovoNordisk and Sanofi.
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Investigators | Contacts |
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Design
- Study design
- Patients' cohort
- Follow Up
- Annual follow-up on disease incidence and mortality. Extensive medical examinations at the start of the study and after 5 years. Annual follow-up of disease incidence and mortality is in progress, comprising (1) collection of information from participants using an annual follow-up questionnaire specifically directed to chronic diseases that occurred in the past year; (2) linking of participant data to hospital and pharmacy records; and (3) collection of mortality data through existing up-to-date databases from Statistics Netherlands (CBS).
Marker Paper
Schram MT, Sep SJ, van der Kallen CJ, Dagnelie PC, Koster A, Schaper N, Henry RM, Stehouwer CD. The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities. Eur J Epidemiol. 2014 Jun;29(6):439-51. doi: 10.1007/s10654-014-9889-0. Epub 2014 Apr 23.
PUBMED 24756374
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 10,000
- Number of participants with biosamples
- Supplementary Information
- T2DM individuals
Access
Availability of data and biosamples
Data | |
Biosamples | |
Other |
Availability of access information
On the study website : https://www.demaastrichtstudie.nl/
By contacting the study representative