The Invecchiare in Chianti study (InCHIANTI)
Initiatives
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The main goal is to translate epidemiological research into geriatric clinical tools that makes possible more precise diagnosis and more effective treatment in older persons with mobility problems. In particular, the plan is:
1. study how the various physiological subsystems that are important for mobility interact with age in causing disability;
2. develop reference values for the integrity and functionality of the different physiologic subsystems that are implicated in mobility, to be used in clinical practice;
3. look at risk factors for the development of “soft” neurological impairments in the absence of neurological disease that is already clinically evident;
4. identify biomarkers of disregulation of the biological network of signals that maintain a stable homeostasis equilibrium after a distressful event, such as a disease or injury;
5. scientific evidence relevant to public health, prevention and intervention trials.
**[email protected]**
- Start Year
- 1997
- End Year
- 2015
- Funding
- Italian Health Ministry and by a NIH contract.
Visit InCHIANTI
Design
- Study design
- Population cohort
- Follow Up
- Baseline (1997). Participants were followed up for over 15 years, the follow ups were conducted in 2002, 2004-2006, 2008 and 2013-2015.
Marker Paper
Cesari M, Pahor M, Bartali B, et al. Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study [published correction appears in Am J Clin Nutr. 2004 Jul;80(1):238]. Am J Clin Nutr. 2004;79(2):289-294. doi:10.1093/ajcn/79.2.289
PUBMED 14749236
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 1,453
- Number of participants with biosamples
- Supplementary Information
- Over 65 years old
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |
Availability of access information
On the study website : http://inchiantistudy.net/wp/