Multi-Ethnic Study of Atherosclerosis
Initiatives
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The objectives of MESA are:
1. To determine characteristics related to progression of subclinical cardiovascular disease (CVD) to clinical CVD;
2. To determine characteristics related to progression of subclinical CVD itself;
3. To assess ethnic, age, and sex differences in subclinical disease prevalence, risk of progression, and rates of clinical CVD;
4. To determine relations of newly identified factors with subclinical disease and to determine their incremental predictive value over established risk factors;
5. To develop methods, suitable for application in future screening and intervention studies, for characterizing risk among asymptomatic persons.
- Start Year
- 1999
- End Year
- 2025
- Funding
- This research is supported by contracts N01-HC-95159 through N01-HC-95169 with the National Heart, Lung, and Blood Institute.
Visit MESA
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Design
- Study design
- Population cohort
- Follow Up
- For classification of CVD events occurring during follow-up in MESA, information will be collected from death certificates, medical records from hospitalizations, autopsy reports, interviews with participants, and, in the case of out-of-hospital deaths, interviews with or questionnaires administered to physicians, relatives, or friends. MESA Assay Census for Exams 1-6( 2002,2004,2005,2007,2011 and 2018)
Marker Paper
Bild DE, Bluemke DA, Burke GL, Detrano R, Diez Roux AV, Folsom AR, Greenland P, Jacob DR Jr, Kronmal R, Liu K, Nelson JC, O'Leary D, Saad MF, Shea S, Szklo M, Tracy RP. Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol. 2002 Nov 1;156(9):871-81. doi: 10.1093/aje/kwf113.
PUBMED 12397006
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 6,814
- Number of participants with biosamples
- Supplementary Information
- Asymptomatic men and women aged 45-84. Approximately 38 percent of the recruited participants are white, 28 percent African-American, 22 percent Hispanic, and 12 percent Asian, predominantly of Chinese descent.
Access
Availability of data and biosamples
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Availability of access information
On the study website : https://www.mesa-nhlbi.org/