Cardiovascular Risk in Young Finns Study
Initiatives
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The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood.
Specific objectives:
* Study the influence of childhood risk factor profile on early atherosclerotic vascular changes and their progression in young adults.
* Study the influence of life-style and life-style changes (diet, physical activity, smoking, alcohol use) on early atherosclerotic vascular changes in young adults.
* Study the influence of behavioral and psychological factors on early atherosclerotic vascular changes in young adults.
* Study the influence of new risk factors, such as oxidized LDL, homocysteine, C-reactive protein, asymmetric dimethylarginine, leptin, adhesion molecules, chlamydia infection on early atherosclerotic vascular changes in young adults.
* Study the influence of gene variation and gene-environment interactions on early atherosclerotic vascular changes in young adults.
* Study risk factor levels and their regional differences
* Study determinants of risk factor levels and the mechanisms how risk factor levels change into adulthood levels
* Study tracking phenomen and risk factor clustering
* Collect background information for primary prevention
- Start Year
- 1980
- End Year
- 2012
- Funding
- Academy of Finland (grants no. 77841, 210283, 34316 and 121584), the Social Insurance Institution of Finland, the Turku University Foundation, Special Federal Grants for the Turku, Tampere and Kuopio University Central Hospital, the Juho Vainio Foundation, Paavo Nurmi Foundation, the Finnish Foundation of Cardiovascular Research, Orion-Farmos Research Foundation and the Finnish Cultural Foundation.
Visit YFS
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Design
- Study design
- Population cohort
- Follow Up
- After the first cross-sectional study in 1980, follow-up studies have been conducted 3 years apart.
Marker Paper
Raitakari OT, Juonala M, Rönnemaa T, Keltikangas-Järvinen L, Räsänen L, Pietikäinen M, Hutri-Kähönen N, Taittonen L, Jokinen E, Marniemi J, Jula A, Telama R, Kähönen M, Lehtimäki T, Akerblom HK, Viikari JS. Cohort profile: the cardiovascular risk in Young Finns Study. Int J Epidemiol. 2008 Dec;37(6):1220-6. doi: 10.1093/ije/dym225. Epub 2008 Feb 8.
PUBMED 18263651
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 3,596
- Number of participants with biosamples
- Supplementary Information
- Total sample size was 4,320 boys and girls in 6 age cohorts (aged 3, 6, 9, 12, 15 and 18).
Access
Availability of data and biosamples
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| Biosamples | |
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Availability of access information
By contacting the study representative