Initiative / interconnect

interconnect

interconnect

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Studies 27
The aim of interconnect is to develop a global data access and results sharing’ network that enables existing data to be readily used in cross-cohort analyses to understand population differences in the risk of diabetes and obesity.
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Investigators Contacts
  • Prof. Nick Wareham
    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE

General Information

Year created
2013
Types of cohorts
  • Population cohort
  • Patient/disease cohort
Region
Europe, America, Australia, Asia, Africa
Setting
International
Funding
EU FP7
Criteria of cohort's to be included
Cohort studies with information of diabetes and obesity.
Health topic
  • General epidemiology
Socio-environmental context
  • NA

Participants

Number of participants

Total
1,000,000
With harmonized data
1,000,000

Methodology for harmonization and integration

Strategy of harmonization
Ex-post
Data processing methods
  • Algorithmic
  • Standardisation
  • Type of infrastructure
    Some centrally, other locally
    Integrative data analysis
    • Meta-analyses
    • Federated analyses
    Software
  • OBiBa (Opal/Mica)
  • DataSHIELD
  • Number of cohorts

    Total
    43
    With harmonized data
    43
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)
    100

    Access

    Availability of metadata
    Under request
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    ARIC Atherosclerosis Risk in Communities Study Population cohort 15,792
    AusDiab Australian Diabetes Obesity and Lifestyle Study Population cohort 11,247
    CARDIA Coronary Artery Risk Development in Young Adults Population cohort 5,115
    CHS Cardiovascular Health Study Population cohort 5,888
    COSM The Cohort of Swedish Men Population cohort 50,000
    FMC Finnish Maternity Cohort Serum Bank Population cohort 2,000,000
    HOORN Hoorn Study Population cohort 2,484
    InterAct EPIC-InterAct Other 28,557
    MESA Multi-Ethnic Study of Atherosclerosis Population cohort 6,814
    NHAPC Nutrition and Health of Aging Population in China Population cohort 3,289
    NOWAC Norwegian Women and Cancer Study Population cohort 165,772
    SMC The Swedish Mammography Cohort Population cohort 61,433
    SUN Cohort Seguimiento University of Navarra Population cohort 22,915
    Zutphen Elderly Study The Zutphen Elderly study - Expansion of the Zutphen cohort Population cohort 939
    ELSA Brasil The Longitudinal Study of Adult Health Population cohort 15,105
    PRHHP Puerto Rico Heart Health Program Population cohort 9,824
    ABCD Amsterdam Born Children and their Development study Population cohort 8,266
    AHS Agricultural Health Study (AHS)private and commercial applicators-USA Population cohort 89,655
    EPIC-Turin European Prospective Investigation into Cancer and Nutrition - Turin Population cohort 10,604
    HSS Healthy Start Study Population cohort 1,410
    MEC Multiethnic Cohort Study Population cohort 215,251
    NHS Nurses' Health Study Population cohort 121,700
    NOMAS The Northern Manhattan Study Population cohort 3,298
    REPRO_PL Polish Mother and Child Cohort Study Population cohort 479
    ROLO Randomized cOntrol trial of LOw glycaemic index diet to prevent the recurrence of macrosomia Clinical trial cohort 800
    WHI Women's Health Initiative Other 161,000
    CKB China Kadoorie Biobank Population cohort 512,891